Physiology of transport mechanisms:
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Mechanisms and regulation of endocytosis in the proximal tubule
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Salt and water handling by distal nephron segments
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Ontogeny and transcriptional regulation of transport systems
- Mechanisms of differentiation of epithelial cells
- Genome-wide association studies for renal function parameters
Pathophysiology of inherited kidney disorders:
- Mechanisms and consequences of proteinuria
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Pathophysiology of inherited forms of chronic interstitial nephritis, including uromodulin-associated kidney disorders
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Gitelman syndrome and salt-losing tubulopathies
- Clinical and genetic aspects of polycystic kidney and liver diseases
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Characterization of mouse models generated by random mutagenesis (ENU)
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Characterization of urinary biomarkers for tubular disorders
Mechanisms of water and solute transport across the peritoneal membrane:
- Improving the efficiency of water and solute removal during peritoneal dialysis
- Role and regulation of water channels in endothelial cells
- Development of mouse models of peritoneal dialysis
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Mechanisms of osmosis, characterization of alternate osmotic agents
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Genetic influence on transport parameters