Oxygen transport and utilization

Representative publications:

The ergogenic effect of recombinant human erythropoietin on VO2max depends on the
severity of arterial hypoxemia.
Robach P, Calbet JA, Thomsen JJ, Boushel R, Mollard P, Rasmussen P, Lundby C. PLoS One. 2008 Aug 20;3(8):e2996.

Does recombinant human Epo increase exercise capacity by means other than
augmenting oxygen transport?
Lundby C, Robach P, Boushel R, Thomsen JJ, Rasmussen P, Koskolou M, Calbet JA. J Appl Physiol. 2008 Aug;105(2):581-7.

Erythropoietin receptor in human skeletal muscle and the effects of acute and
long-term injections with recombinant human erythropoietin on the skeletal muscle.
Lundby C, Hellsten Y, Jensen MB, Munch AS, Pilegaard H. J Appl Physiol. 2008 Apr;104(4):1154-60.

During hypoxic exercise some vasoconstriction is needed to match O2
delivery with O2 demand at the microcirculatory level.
Lundby C, Boushel R, Robach P, Møller K, Saltin B, Calbet JA. J Physiol. 2008 Jan 1;586(1):123-30.

Strong iron demand during hypoxia-induced erythropoiesis is associated with down-regulation of iron-related proteins and myoglobin in human skeletal muscle.
Robach P, Cairo G, Gelfi C, Bernuzzi F, Pilegaard H, Viganò A, Santambrogio P, Cerretelli P, Calbet JA, Moutereau S, Lundby C. Blood. 2007 Jun 1;109(11):4724-31.

Erythropoietin treatment elevates haemoglobin concentration by increasing red cell volume and depressing plasma volume.
Lundby C, Thomsen JJ, Boushel R, Koskolou M, Warberg J, Calbet JA, Robach P. J Physiol. 2007 Jan 1;578(Pt 1):309-14

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