Cellular Oxygen Physiology
Most relevant publications of the last few years
ORIGINAL ARTICLES
*Storti F., *Santambrogio S., Crowther L.M., Otto T., Abreu-Rodríguez I., Kaufmann M., Hu Ch-J., Dame Ch., Fandrey J., Wenger R.H., Hoogewijs D.
A novel distal upstream hypoxia response element regulating oxygen-dependent erythropoietin gene expression.
Haematologica 2014, 99:e45-49. *joint first authors
Kaufmann M.R., Barth S., Konietzko U., Wu B., Egger S., Kunze R., Marti H.H., Hick M., Müller U., Camenisch G., Wenger R.H.
Dysregulation of Hypoxia-Inducible Factor by Presenilin/γ-Secretase Loss-of-Function Mutations
J Neurosci 2013, 33(5), 1915-1926.
Wollenick K., Hu J., Kristiansen G., Schraml P., Rehrauer H., Berchner-Pfannschmidt U., Fandrey J., Wenger R.H., Stiehl D.P.
Synthetic transactivation screening reveals ETV4 as broad coactivator of hypoxia-inducible factor signaling.
Nucl Acids Res 2012, 1-16.
Ladroue Ch.*,Hoogewijs D.*, Gad S., Carcenac R., Storti F., Barrois M., Gimenez-Roqueplo A.P., Leporrier M., Casadevall N., Hermine O., Kiladjian J.J., Baruchel A., Fakhoury F., Bressac-de Paillerets B., Feunteun J., Mazure N., Pouysségur J., Wenger R.H., Richard St., Gardie B.
Distinct deregulation of the hypoxia inducible factor by PHD2 mutants identified in germline DNA of patients with polycythemia.
Haematologica 2012, 97, 9-14. *joint first authors
Hoogewijs D., Ebner B., Germani F., Hoffmann, F.G., Fabrizius A., Moens L., Burmester T., Dewilde S., Storz J.F., Vinogradov S.N., Hankeln T.
Androglobin: A Chimeric Globin in Metazoans That Is Preferentially Expressed in Mammalian Testes.
Mol Biol Evol 2012, 4, 1105-1114.
Stiehl D.P., Bordoli M.R., Abreu-Rodríguez I., Wollenick K., Schraml P., Gradin K., Poellinger L., Kristiansen G., Wenger R.H.
Non-canonical HIF-2alpha function drives autonomous breast cancer cell growth via an AREG-EGFR/ErbB4 autocrine loop.
Oncogene 2012, 31, 2283-2297.
Nytko K.J., Maeda N., Schläfli Ph., Spielmann P., Wenger R.H., Stiehl D.P.
Vitamin C is dispensable for oxygen sensing in vivo.
Blood 2011, 117(20), 5485-5493.
Bordoli M.R., Stiehl D.P., Borsig L., Kristiansen G., Hausladen S., Schraml P., Wenger R.H., Camenisch G.
Prolyl-4-hydroxylase PHD2- and hypoxia-inducible factor 2-dependent regulation of amphiregulin contributes to breast tumorigenesis.
Oncogene 2011, 30, 548-560.
Balamurugan K., Luu V-D., Kaufmann M.R., Hofmann V.S., Boysen G., Barth S., Bordoli M.R., Stiehl D.P., Moch H., Schraml P., Wenger R.H. and Camenisch G.
Onconeuronal cerebellar degeneration-related antigen, Cdr2, is strongly expressed in papillary renal cell carcinoma and leads to attenuated hypoxic response.
Oncogene 2009, 28, 3274-3285.
Barth S., Edlich F., Berchner-Pfannschmidt U., Gneuss S., Jahreis G., Hasgall Ph.A., Fandrey J., Wenger R.H., Camenisch G.
Hypoxia-inducible Factor Prolyl-4-hydroxylase PHD2 Protein Abundance Depends on Integral Membrane Anchoring of FKBP38.
J Biol Chem 2009, 284, 23046-23058.
REVIEWS
Wenger R.H., Kurtz A.
Erythropoietin
Compr Physiol 2011, 1, 1759-1794.
Wenger R.H., Hoogewijs D.
Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells
Am J Physiol Renal Physiol 2010, 298, F1287–F1296.
Wenger R.H., Camenisch G., Stiehl D.P., Katschinski D.M.
HIF Prolyl-4-hydroxylase Interacting Proteins: Consequences for Drug Targeting
Curr. Pharm. Design 2009, 15, 3886-3894.
Schläfli P., Borter E., Spielmann P. and Wenger R.H.
The PAS-domain kinase PASKIN: a new sensor in energy homeostasis.
Cell Mol Life Sci 2009, 66, 876-883.
for more use MedLine in the Link section