Publications (since 2010)
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Publications
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COVID-19 is, in the end, an endothelial disease European Heart Journal, 41(32):3038-3044.
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Genetic and Clinical Predictors of Age of ESKD in Individuals With Autosomal Dominant Tubulointerstitial Kidney Disease Due to UMOD Mutations Kidney International Reports, 5(9):1472-1485.
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Architecture and function of human uromodulin filaments in urinary tract infections Science, 369(6506):1005-1010.
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Non-canonical signalling by the cellular oxygen sensor Factor Inhibiting HIF (FIH) 2020, University of Zurich, Medizinische Fakultät.
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Mechanisms of cognitive dysfunction in CKD Nature Reviews. Nephrology, 16(8):452-469.
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Simultaneous three-dimensional vascular and tubular imaging of whole mouse kidneys with X-ray μCT Microscopy and Microanalysis, 26(4):731-740.
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Coming out of the PiTs-novel strategies for controlling intestinal phosphate absorption in patients with CKD Kidney International, 98(2):273-275.
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Emergence and significance of carbohydrate-specific antibodies Genes and immunity, 21(4):224-239.
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Contribution of the Gut Microbiota to the Origin of Carbohydrate-Specific Antibodies 2020, University of Zurich, Medizinische Fakultät.
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Renal handling of zinc in chronic kidney disease patients and the role of circulating zinc levels in renal function decline Nephrology, Dialysis, Transplantation, 35(7):1163-1170.
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Gerhard Giebisch (1927-2020): A Leader in Kidney Physiology Journal of the American Society of Nephrology (JASN), 31(7):1419-1420.
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A patient with chronic kidney disease, primary biliary cirrhosis and metabolic acidosis Clinical Kidney Journal, 13(3):463-467.
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Methylmalonyl acidemia: from mitochondrial metabolism to defective mitophagy and disease Autophagy, 16(6):1159-1161.
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Early experience with COVID-19 in kidney transplantation Kidney International, 97(6):1074-1075.
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The anti-oxidative role of cytoglobin in podocytes: implications for a role in chronic kidney disease Antioxidants & Redox Signaling, 32(16):1155-1171.
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Tubular β-catenin and FoxO3 interactions protect in chronic kidney disease Journal of Clinical Investigation Insight, 5(10):e135454.
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Mitochondria, mitophagy, and metabolic disease: towards assembling the puzzle Cell Stress, 4(6):147-150.
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An expert update on novel therapeutic targets for hyperphosphatemia in chronic kidney disease: preclinical and clinical innovations Expert Opinion on Therapeutic Targets, 24(5):477-488.
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The first decade of Kidney International: treasure hunt for the kidney tubule Kidney International, 97(5):818-822.
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Sevoflurane sedation attenuates early cerebral oedema formation through stabilisation of the adherens junction protein beta catenin in a model of subarachnoid haemorrhage : A randomised animal study European Journal of Anaesthesiology, 37(5):402-412.
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Crosslinkable polymeric contrast agent for high-resolution X-ray imaging of the vascular system Chemical Communications, 56(44):5885-5888.
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Cre-mediated, loxP independent sequential recombination of a tripartite transcriptional stop cassette allows for partial read-through transcription Biochimica et Biophysica Acta. Gene Regulatory Mechanisms, 1863(8):194568.
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Parathyroid hormone and plasma phosphate are predictors of soluble α-klotho levels in adults of European descent Journal of Clinical Endocrinology & Metabolism, 105(4):dgz232.
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Expression of NaPi-IIb in rodent and human kidney and upregulation in a model of chronic kidney disease Pflügers Archiv : European Journal of Physiology, 472(4):449-460.
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Choroid plexus LAT2 and SNAT3 as partners in CSF amino acid homeostasis maintenance Fluids and Barriers of the CNS, 17:17.
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Next-generation sequencing for detection of somatic mosaicism in autosomal dominant polycystic kidney disease Kidney International, 97(2):261-263.
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Potassium channels in control of renal function. Kidney International, 97(2):253-255.
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HIF hydroxylase inhibitors decrease cellular oxygen consumption depending on their selectivity FASEB Journal, 34(2):2344-2358.
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TGFβ Signaling in Myeloid and Endothelial Cells Is Required for Lung and Liver Metastasis 2020, University of Zurich, Faculty of Science.
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Impaired endothelium-mediated cerebrovascular reactivity promotes anxiety and respiration disorders in mice Proceedings of the National Academy of Sciences of the United States of America, 117(3):1753-1761.
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Rapid cellular perception of gravitational forces in human jurkat T cells and transduction into gene expression regulation International Journal of Molecular Sciences, 21(2):514.
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Metabolic Acidosis Alters Expression of Slc22 Transporters in Mouse Kidney Kidney & Blood Pressure Research, 45(2):263-274.
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Heparanase in Cancer Metastasis - Heparin as a Potential Inhibitor of Cell Adhesion Molecules In: Bendas, Gerd; Borsig, Lubor . Heparanase : From Basic Research to Clinical Applications. Cham: Springer, 309-329.
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Characterization of the Physiological Role of the Deubiquitinase OTUB1 in Mice 2020, University of Zurich, Faculty of Science.
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Mechanisms of the Anti-Apoptotic Effect of High-Density Lipoproteins and Its Components on Pancreatic beta-Cells 2020, University of Zurich, Faculty of Science.
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Mild cognitive impairment and kidney disease: clinical aspects Nephrology, Dialysis, Transplantation, 35(1):10-17.
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SARS-CoV-2 receptor ACE2 gene expression in small intestine correlates with age Amino acids, 52(6-7):1063-1065.
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The Urinary Excretion of Uromodulin is Regulated by the Potassium Channel ROMK Scientific Reports, 9:19517.
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Differential impact of dietary branched chain and aromatic amino acids on chronic kidney disease progression in rats Frontiers in Physiology, 10:x.
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High-throughput sequencing contributes to the diagnosis of tubulopathies and familial hypercalcemia hypocalciuria in adults Kidney International, 96(6):1408-1416.
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Genome-wide association meta-analyses and fine-mapping elucidate pathways influencing albuminuria Nature Communications, 10(1):4130.
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Hepsin-mediated Processing of Uromodulin is Crucial for Salt-sensitivity and Thick Ascending Limb Homeostasis Scientific Reports, 9:12287.
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Low infiltration of tumor-associated macrophages in high c-Myb-expressing breast tumors Scientific Reports, 9(1):11634.
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Autosomal dominant tubulointerstitial kidney disease Nature Reviews. Disease Primers, 5:60.
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Biochemical functionality of magnetic particles as nanosensors: how far away are we to implement them into clinical practice? Journal of Nanobiotechnology, 17:73.
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Reduced-order modeling of blood flow for noninvasive functional evaluation of coronary artery disease Biomechanics and Modeling in Mechanobiology, 18(6):1867-1881.