Cell Physiology and Glycobiology

Hartmann K.P., van Gogh M., Freitag P.C., Kast F., Nagy-Davidescu G., Borsig .L, Plückthun A.

FAP-retargeted Ad5 enables in vivo gene delivery to stromal cells in the tumor microenvironment.

Mol Ther. 2023 Aug 28:S1525-0016(23)00451-3. doi: 10.1016/j.ymthe.2023.08.018.

Van Gogh M., Glaus Garzon J.F., Sahin D., Knopfova L., Benes P., Boyman O., Jurisica I., Borsig L.

Tumor cell-intrinsic c-Myb upregulation stimulates anti-tumor immunity in a murine colorectal cancer model.

Cancer Immunol Res (2023). doi: 10.1158/2326-6066.CIR-22-0912

Mele V., Governa V., Glaus Garzon J.F., Muraro M.G., Oertle P., Däster S., Nebiker C., Mechera R., Oertli D., Rosso R., Bolli M., Lugli A., Terracciano L.M., Schmidt A., Plodinec M., Spagnoli G.C., Borsig L., Iezzi G.

Identification of TPM2 and CNN1 as Novel Prognostic Markers in Functionally Characterized Human Colon Cancer-Associated Stromal Cells.

Cancers 14:2024. doi: 10.3390/cancers14082024. (2022)

Stefanescu C., van Gogh M, Roblek M., Heikenwälder M., Borsig L.

TGFβ signaling in myeloid cells promotes lung and liver metastasis through different mechanisms.

Front Oncol 11:765151 (2021)

Bertok T., Bertokova A., Jane E., Hires M., Aguedo J., Potocarova M., Lukac L., Vikartovska A., Kasak P., Borsig L., Tkac J.

Identification of a whole-serum glycomarkers for colorectal carcinoma using reverse-phase lectin microarray.

Front Oncol. 11:735338 (2021)

Montalban-Arques A., Katkeviciute E., Busenhart P., Bircher A., Wirbel J., Zeller G., Morsy Y., Borsig L., Glaus Garzon L., Müller A., Arnold I.C., Artola-Boran M., Krauthammer M., Sintsova A., Zamboni N., Leventhal G.E., Berchtold L., de Wouters T., Rogler G., Baebler K., Schwarzfischer M., Hering L., Olivares- Rivas I., Atrott K., Gottier C., Lang S., Boyman O., Fritsch R., Manz M.G., Spalinger M.R., Scharl M.

Commensal Clostridiales strains mediate effective anti-cancer immune response against solid tumors.

Cell Host Microbe 29:1573-88 (2021).

Dúcka M., Kučeríková M., Trčka F., Červinka J., Biglieri E., Šmarda J., Borsig L., Beneš P., Knopfová L.

c-Myb interferes with inflammatory IL1α-NF-κB pathway in breast cancer cells.

Neoplasia 23:326-36 (2021)

Glaus Garzon J.F., Pastrello C., Jurisica I., Hottiger M.O., Wenger R.H., Borsig L.

Tumor cell endogenous HIF-1a activity induces aberrant angiogenesis and interacts with TRAF6 pathway required for colorectal cancer development

Neoplasia 22:745-758 (2020)

Sahin D., Arenas-Ramirez N., Rath M., Karakus U., Hümbelin M., van Gogh M., Borsig L., Boyman O.

A novel IL-2-grafted antibody immunotherapy with potent efficacy against metastatic cancer

Nat Commun. 11(1):6440 (2020)

Roblek M., Protsyuk D., Becker P., Stefanescu C., Gorzelanny C., Glaus Garzon J., Knopfova L., Heikenwalder M., Lückow B., Schneider S.W. Borsig L.

CCL2 is a vascular permeability factor inducing endothelial retraction during lung metastasis

Mol Cancer Res 17:783-793 (2019)

Bendas G, Borsig L.

Heparanase in Cancer Metastasis - Heparin as a Potential Inhibitor of Cell Adhesion Molecules.

Adv Exp Med Biol. 1221:309-329 (2020)

Laubli H., Borsig L.

Altered cell adhesion and glycosylation promote cancer immune suppression and metastasis

Front Immunol. 10:2120 (2019)

Borsig L.

Selectins in cancer immunology

Glycobiology 28:648-655 (2018)