Cellular Oxygen Physiology

Most relevant publications of the last few years


Imeri F., Nolan K.A., Bapst A.M., Santambrogio S., Abreu-Rodriguez I., Spielmann P., Pfundstein S., Libertini S.,
Crowther L., Orlando I.M.C., Dahl S.L., Keodara A., Kuo W., Kurtcuoglu V., Scholz C.C., Weihong Q., Hummler E.,
Hoogewijs D., Wenger R.H.
Generation of renal Epo-producing cell lines by conditional gene tagging reveals rapid HIF-2 driven Epo kinetics,
cell autonomous feedback regulation, and a telocyte phenotype

Kidney Int 2019, 95: 375-387


Pickel C., Taylor CT., Scholz C.
Genetic Knockdown and Pharmacologic Inhibition of Hypoxia-Inducible Factor (HIF) Hydroxylases
Methods Mol Biol 2018, 1742: 1-14


Cosin-Roger J., Simmen S., Melhem H., Atrott K., Frey-Wagner I., Hausmann M., de Vallière Ch., Spalinger M.R.,
Spielmann P., Wenger R.H., Zeitz J., Vavricka S. R., Rogler G., Ruiz P.A.
Hypoxia ameliorates intestinal inflammation through NLRP3/mTOR downregulation and autophagy activation
Nat Commun 2017, 8:98

Günter J., Ruiz-Serrano A., Pickel C., Wenger RH., Scholz CC.
The functional interplay between the HIF pathway and the ubiquitin system - more than a one-way road
Exp Cell Res 2017, 356 (2): 152-159


Gutsche K., Randi E.B., Blank V., Fink D., Wenger R.H., Leo C., Scholz C.C.
Intermittent hypoxia confers pro-metastatic gene expression selectively through NF-κB in inflammatory
breast cancer cells

Free Radical Biology and Medicine, 2016, 101, 129-142

Fuady J.H., Gutsche K., Santambrogio S., Varga Z., Hoogewijs D., Wenger R.H.
Estrogen-dependent downregulation of hypoxia-inducible factor (HIF)-2a in invasive breast cancer cells
Oncotarget 2016, 7(21):31153-65

Scholz C.C., Rodriguez J., Pickel C., Burr S., Fabrizio J.-A., Nolan, K.A., Spielmann P., Cavadas M.A.S., Crifo B.,
Halligan D.N., Nathan J.A., Peet D.J., Wenger R.H., Von Kriegsheim A., Cummins E.P., Taylor C.T.
FIH regulates cellular metabolism through hydroxylation of the deubiquitinase OTUB1
PLoS Biol. 2016, 14, e1002347

Schörg A., Santambrogio S., Platt J., Schödel J., Lindenmeyer M.T., Cohen C.D., Schrödter K., Mole D.R., Wenger R.H.,
Hoogewijs D.
Destruction of a distal hypoxia response element abolishes trans-activation of the PAG1 gene mediated
by HIF-independent chromatin looping

Nucleic Acids Res. 43, 2015: 5810-5823


Wenger R.H., Kurtcuoglu V., Scholz C.C., Marti H.H., Hoogewijs D.
Frequently asked questions in hypoxia research
Hypoxia 2015,  3, 35-43

Wenger R.H., Kurtz A.
Compr Physiol 2011, 1, 1759-1794

Wenger R.H., Hoogewijs D.
Regulated oxygen sensing by protein hydroxylation in renal erythropoietin-producing cells
Am J Physiol Renal Physiol 2010, 298, F1287–F1296












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